Principal Scientist - Genomics (Temporary Contract) Full-time Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. The purpose of this position is to develop high-throughput cutting-edge genomic technologies to better understand disease mechanisms and to accelerate the discovery of new targets and biomarkers across therapeutic areas. The incumbent will utilize innovative genetic screening (CRISPR) and multi-omics single cell sequencing approaches (Optical pooled screening, CRISPR-Seq) to impact all stages of the pipeline from pre-clinical to clinical development. In the position, you will collaborate closely with Oncology, Immunology, Neuroscience, Cardiometabolic disease, Pharmacology, and Chemical Biology areas throughout the Discovery, Preclinical and Translational Medicine. We are seeking a highly motivated scientist with expertise in cell and molecular biology, high-throughput genomic technologies, CRISPR screening, and high content imaging to join our group in Cambridge, MA. In this exciting role you will: Contribute to the planning and execution of experiments to discover new drug targets in multiple therapeutic areas. Work with complex cellular models (primary cells, iPSC-derived cells, 2D and 3D coculture models) in addition to immortalized cell lines. Assist in developing, executing, analyzing, and troubleshooting new cell-based assays with disease-relevant phenotypes and determine feasibility and the best approach for CRISPR screens. Execute large-scale CRISPR screens in pooled and arrayed formats. Use gene editing and other genomic technologies (transcriptomics, proteomics) to validate potential drug targets. Communicate results and findings clearly and concisely to teams and stakeholders. Maintain detailed lab notebook and records of work, help the lab manager maintain laboratory equipment used for experiments. This position requires 90% of time in the lab. Minimum Qualifications: Ph.D. degree in cell and molecular biology or related scientific discipline or M.S. degree in cell and molecular biology or related scientific discipline with 5+ years hands-on wet lab experience in academia or industry. Required Experience and Skills: Extensive hands-on experience in cell-based assay development, CRISPR-based screens. Working knowledge and experience with high-content imaging assays. Strong ability to troubleshoot and optimize novel methods and protocols. Self-motivated and capable of prioritizing deliverables among multiple simultaneous projects. Excellent attention to detail and strong communication skills. Ability to work independently, but also build strong relationships within highly collaborative, multidisciplinary teams to effectively drive early drug discovery initiatives. Preferred Experience and Skills: Demonstrated experience with high-content phenotypic screening. Image analysis tools experience (e.g. Signals Image Artist). Experience with genomic technologies (NGS, scRNA-seq, CROP-seq/Perturb-seq). Drug Discovery experience in biotech and/or pharmaceutical industry. Experience working in a highly matrixed organization. The position is a temporary role, Monday-Friday from 8am-5pm. Candidates living within a commutable distance of Boston, MA and the surrounding areas are encouraged to apply. Excellent full-time benefits including comprehensive medical coverage, dental, and vision options. Life and disability insurance. 401(k) with company match. Paid vacation and holidays. Eurofins is an M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer. #J-18808-Ljbffr Eurofins BioPharma Product Testing Ireland, Ltd.
...Maintain liaison with residents and family members. Follow work assignments and/or work schedules in completing and performing tasks. Requirements: High school or equivalent (Required) Medication Tech Certification (Required) Equal Opportunity Employer #LY71
...records to obtain facts to resolve all material issues in a case or to establish the background, reputation, character, suitability, or qualifications of the subject under investigation. Independent Contractors are not employees and have the ability to accept and...
Join our team of more than 34,000 team members, supporting our members and communities in our Club Support Center, 235+ clubs and eight distribution centers. BJs Wholesale Club offers a collaborative and inclusive environment where all team members can learn, grow and...
...Job Description &##128680; We're Hiring a Part-Time Registered Nurse (RN)! &##128680; Senior Helpers of North Hudson is looking for a compassionate and skilled RN to join our team! If you're passionate about home care and want a flexible, part-time opportunity...
...We are looking to add a key member to our digital team, who can manage and execute our clients digital ad platforms, predominantly paid Meta... ...digital advertising strategy and execution of the digital marketing campaigns for a variety of clients. Immerse Agency is...